The correct choice is Deploy a gateway VPC endpoint for Amazon S3 and update the subnet route table to use it and restrict access with a bucket or IAM policy tied to the endpoint. This option directs the EC2 instance to upload to S3 over the AWS private network instead of using the public internet.

The gateway VPC endpoint creates VPC routes that send S3 traffic through the AWS backbone. You can attach endpoint policies or use bucket policies that reference the endpoint to restrict which principals or subnets may access the bucket. This approach normally requires no changes to the application and achieves the goal of keeping data transfers internal to AWS.

Create an S3 access point in the same Region, grant the instance role access, and update the application to use the access point alias is incorrect because access points simplify and scope access but they do not by themselves change the network path to S3. Without a VPC endpoint the uploads would still traverse public S3 endpoints.

Enable S3 Transfer Acceleration on the bucket and update the application to use the acceleration endpoint is incorrect because Transfer Acceleration uses public edge locations to speed up transfers and it does not provide private VPC connectivity.

Order an AWS Direct Connect dedicated connection and route VPC traffic to Amazon S3 over it is unnecessary and usually cost prohibitive for this requirement. Direct Connect is intended for private connectivity between on premises and AWS and it is not the typical solution to keep EC2 to S3 traffic inside the AWS network when a gateway VPC endpoint is available.

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